Description IL-18 (Interleukin-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. It signals through a heterodimeric receptor composed of IL-18Rα (binding chain) and IL-18Rβ (signaling chain), leading to...

Description IL-18 is a pleiotropic proinflammatory cytokine belonging to the IL-1 superfamily, which requires caspase-1-mediated proteolytic activation to engage the heterodimeric IL-18Rα/β receptor, triggering NF-κB and MAPK signaling pathways that...

Description IL-1α (Interleukin-1α), a key member of the interleukin-1 (IL-1) family, shares a similar β-trefoil topology with other IL-1 family members such as IL-1β, despite low sequence homology. Like IL-1β,...

Description IL-1β (Interleukin-1β) is a key pro-inflammatory cytokine that plays a central role in immune regulation, inflammatory responses, and cellular signaling. The mature form of IL-1β adopts a β-trefoil structure...

Description IL-1α is a pleiotropic proinflammatory cytokine and core member of the IL-1 superfamily. Constitutively expressed as a precursor in epithelial cells (particularly dermal keratinocytes), it is proteolytically activated by...

Description Recombinant human IL-1β protein, a high-purity pro-inflammatory cytokine produced in an E. coli expression system and precisely refolded to retain its native bioactivity, exerts a central role in innate...

Description Recombinant Human Interleukin-2 (IL-2) is a cytokine that plays a central role in the regulation of immune responses. It is primarily produced by activated T lymphocytes and promotes the...

Description Activated T cells generally cannot survive for a long time in vitro culture, and the addition of IL-2 can promote their long-term and sustained proliferation. The surface of stationary...