Description Recombinant Human Interleukin-3 (IL-3) is a crucial cytokine involved in the regulation of hematopoiesis, stimulating the proliferation and differentiation of various blood cells. IL-3 exerts its effects by binding...
Description IL-33 (Interleukin-33) is a cytokine belonging to the IL-1 family and is mainly expressed by epithelial cells, endothelial cells, and fibroblasts. It signals through the ST2 (IL-1RL1) receptor in...
Description IL-4 (Interleukin-4) is a cytokine primarily secreted by Th2 cells, mast cells, and basophils. It functions by binding to receptor complexes such as IL-4Rα/γc or IL-4Rα/IL-13Rα1, activating the JAK-STAT6...
Description As a master regulator of Th2 immunity, IL-4 activates the JAK1/3-STAT6 signaling cascade via the IL-4Rα/γc receptor complex, directing naive CD4+ T-cell differentiation into Th2 effectors secreting IL-5/IL-13 while...
Description IL-5 (Interleukin-5) is a Th2-associated cytokine primarily produced by Th2 cells, type 2 innate lymphoid cells (ILC2s), and mast cells. It signals through the IL-5 receptor complex composed of...
Description IL-6 (Interleukin-6) is a pleiotropic cytokine secreted by various cell types, including T cells, B cells, macrophages, fibroblasts, and endothelial cells. It plays a critical role in immune regulation,...
Description Recombinant human interleukin-6 (IL-6) is a pleiotropic cytokine that plays a central role in immune regulation, inflammatory responses, and hematopoietic modulation. This recombinant protein can serve as an antigen...
Description The recombinant human IL-6- protein is produced in HEK-293 cells via transient transfection, featuring a C-terminal polyhistidine (His) tag for nickel-affinity purification. As a pleiotropic α-helical cytokine, IL-6 activates...