Biofargo News & Blog

The Biology of cccDNA — Why Topology Matters To understand why isolating cccDNA is technically demanding, it helps to understand what makes it structurally distinct — and why that distinction has such...

eccDNA as a Cancer Biomarker — What Researchers Need to Know Extrachromosomal circular DNA was, for decades, an interesting molecular curiosity with limited clinical relevance. That picture has changed substantially over the...

Why Enzyme-Free cccDNA Isolation Changes Your HBV Research For researchers studying hepatitis B virus (HBV) or extrachromosomal circular DNA (eccDNA), the isolation of covalently closed circular DNA (cccDNA) has always been one...

Fast Green FCF: Four Protocols Where This Dye Quietly Outperforms the Alternatives A closer look at one of the most underused stains in the molecular biology toolkit — and why it belongs...

How to Improve RNA Extraction Consistency in Your Lab Establishing a robust foundation for reproducible genomic research Reproducibility is the foundation of reliable science. Yet for many labs, RNA extraction remains one...

Phase Lock Gel vs Phase Gel Tubes: Which One Should You Choose? If you've been researching ways to improve your phenol/chloroform extraction workflow, you've likely come across both Phase Lock Gel and...