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06
Jan
Polysorbate‑80 in Pharmaceutical and Biotech Formulations
Insights for Pharmaceutical and Biotech Researchers
Polysorbate‑80 (Tween‑80) is a high-purity non-ionic surfactant widely used in pharmaceutical and biotechnological formulations. Its excellent emulsifying, solubilizing, and stabilizing properties make it essential in vaccines, protein therapeutics, and other biologics. This article explores its roles, applications, and industry benefits.
Pharmaceutical Applications
Tween‑80 is commonly applied in pharmaceutical products for its ability to stabilize active ingredients and prevent aggregation. Key applications include:
- 💊 Injectable formulations: Maintains solubility and uniformity of hydrophobic drugs.
- 💉 Vaccine stabilizer: Protects proteins and antigens during storage and transport.
- 🧪 Oral and topical formulations: Improves dispersion and absorption of active compounds.
Biotech and Biologic Applications
In biologics, Tween‑80 plays a crucial role in maintaining protein stability and preventing denaturation. Applications include:
- 🔬 Protein therapeutics: Reduces surface adsorption and aggregation.
- 🧫 Vaccine formulations: Protects antigen structure during manufacturing and storage.
- ⚗️ Cell culture additives: Improves solubility of hydrophobic supplements or small molecules.
Key Benefits in Pharmaceutical and Biotech Formulations
Protein Stabilization
Prevents aggregation and maintains biologic activity during processing and storage.
Enhanced Solubility
Facilitates dispersion of hydrophobic active ingredients in aqueous formulations.
Regulatory Compliance
Pharmaceutical grade ensures safety and reliability for clinical and industrial use.
Industry Case Highlights
Examples of Tween‑80 in industry:
- 💉 Stabilizing influenza and COVID-19 vaccines during storage and transport.
- 🔬 Enhancing protein therapeutic formulations for long-term stability.
- ⚗️ Improving solubility of hydrophobic adjuvants and excipients in biotech formulations.
Why Choose Biofargo Pharmaceutical Grade Tween‑80
High Purity
Meets pharmaceutical standards for vaccines and protein therapeutics.
Reliable Supply
Consistent quality ensures reproducibility and regulatory compliance.
Versatile Applications
Suitable for vaccines, protein therapeutics, and biotech formulations.
Learn more on the Biofargo Pharmaceutical Grade Tween‑80 product page.
Biofargo team
