Bcakground Sonic Hedgehog (Shh) is expressed in embryonic tissues that are critical for the patterning of the developing central nervous system, somite, and limb. It is also involved in whisker,...
Bcakground Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central...
Bcakground CD40 Ligand (CD40L), also known as TNFSF, CD154, TRAP, and gp39, is a 34–39 kDa type II transmembrane glycoprotein that belongs to the TNF superfamily (1–3). Mature human CD40...
Bcakground Interon-alpha (IFN-alpha),also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I...
TROP-2 is a cell surface glycoprotein highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors. The human TROP-2 protein is composed of...
Bcakground FGF basic(FGF-2)is a member of the FGF superfamily of mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic are unique from other members of the family...
Bcakground Fibroblast growth factor-7(FGF-7) is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, morphogenesis, angiogenesis, wound healing, and...
Bcakground FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation (1-3). Unlike other FGFs, FGF acidic and...