Description The recombinant human IL-12 fusion protein is a heterodimer produced by transient transfection in HEK-293 cells, consisting of an IL-12A (p35) subunit with a 6×his-tag and an IL-12B (p40)...

Description IL-15 (Interleukin-15) is a pleiotropic cytokine belonging to the common gamma-chain (γc) cytokine family. While structurally similar to IL-2, it exhibits distinct functional properties. It is primarily produced by...

Description The recombinant human IL-15 fusion protein is a genetically engineered chimeric immunomodulatory molecule constructed by tandem fusion of the IL-15 cytokine core, sushi domain of IL-15 receptor α (IL-15Rα),...

Description IL-17A (Interleukin-17A) is a pro-inflammatory cytokine mainly produced by Th17 cells, as well as γδ T cells and innate lymphoid cells. It signals through the IL-17RA/IL-17RC receptor complex, activating...

Description IL-18 (Interleukin-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. It signals through a heterodimeric receptor composed of IL-18Rα (binding chain) and IL-18Rβ (signaling chain), leading to...

Description IL-18 is a pleiotropic proinflammatory cytokine belonging to the IL-1 superfamily, which requires caspase-1-mediated proteolytic activation to engage the heterodimeric IL-18Rα/β receptor, triggering NF-κB and MAPK signaling pathways that...

Description IL-1α (Interleukin-1α), a key member of the interleukin-1 (IL-1) family, shares a similar β-trefoil topology with other IL-1 family members such as IL-1β, despite low sequence homology. Like IL-1β,...

Description IL-1β (Interleukin-1β) is a key pro-inflammatory cytokine that plays a central role in immune regulation, inflammatory responses, and cellular signaling. The mature form of IL-1β adopts a β-trefoil structure...