Description A fragment encompassing domains ED1+2 of the Chikungunya virus E1 protein is involved in the fusion process between the viral envelope and the host cell endosomal membrane and contains...
Description IL-6 (Interleukin-6) is a pleiotropic cytokine secreted by various cell types, including T cells, B cells, macrophages, fibroblasts, and endothelial cells. It plays a critical role in immune regulation,...
Description IL-6 (Interleukin-6) is a pleiotropic cytokine secreted by various cell types, including T cells, B cells, macrophages, fibroblasts, and endothelial cells. It plays a critical role in immune regulation,...
Description IL-17A (Interleukin-17A) is a pro-inflammatory cytokine mainly produced by Th17 cells, as well as γδ T cells and innate lymphoid cells. It signals through the IL-17RA/IL-17RC receptor complex, activating...
Description IL-33 (Interleukin-33) is a cytokine belonging to the IL-1 family and is mainly expressed by epithelial cells, endothelial cells, and fibroblasts. It signals through the ST2 (IL-1RL1) receptor in...
Description IL-6 (Interleukin-6) is a pleiotropic cytokine secreted by various cell types, including T cells, B cells, macrophages, fibroblasts, and endothelial cells. It plays a critical role in immune regulation,...
Description IL-4 (Interleukin-4) is a cytokine primarily secreted by Th2 cells, mast cells, and basophils. It functions by binding to receptor complexes such as IL-4Rα/γc or IL-4Rα/IL-13Rα1, activating the JAK-STAT6...
Description IL-1α (Interleukin-1α), a key member of the interleukin-1 (IL-1) family, shares a similar β-trefoil topology with other IL-1 family members such as IL-1β, despite low sequence homology. Like IL-1β,...