Description CNTF (Ciliary Neurotrophic Factor) is a neurotrophic factor structurally similar to IL-6 and LIF, featuring a characteristic four-helix bundle topology. It was initially identified based on its ability to...
Description FGF-2 (Fibroblast Growth Factor-2 (Basic)), also known as bFGF, is one of the earliest recognized members of the FGF family. Secreted by endothelial cells, smooth muscle cells, and macrophages,...
Description Transferrin is an important glycoprotein composed of two domains, each containing an iron-binding site—one at the N-terminus and one at the C-terminus. Each site can bind one Fe³⁺ ion...
Description TGF-β3 (Transforming Growth Factor-β3) is a pleiotropic cytokine within the TGF-β superfamily that plays important roles in embryonic development, tissue repair, immune regulation, and cell differentiation. Unlike TGF-β1, which...
The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes,...
Bcakground Interferon-gamma (IFN-gamma) , also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2)....
Bcakground Recombinant mouse LIF (leukemia inhibitory factor) is commonly used in cell culture to maintain the pluripotency of stem cells. LIF is a widely expressed pleiotropic member of the IL-6...
Description PDGF-BB (Platelet-Derived Growth Factor-BB) is an important growth factor belonging to the platelet-derived growth factor (PDGF) family. It consists of two identical B chains linked by disulfide bonds to...