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Sku: P114352-50 μl

Specification

Full name OPRM1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.
Swissprot No P35372
Gene Accession NP_000905
WB Predicted band size
WB Positive control P114352-WB-1-P
WB Recommended dilution 44 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114352-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or OPRM1 antigen-treated (Neutralization experiment) using P114352(OPRM1 Antibody) at dilution 1/50

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