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Sku: P114596-50 μl

Specification

Full name NQO1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Swissprot No P15559
Gene Accession NP_000894
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using P114596(NQO1 Antibody) at dilution 1/35
WB Positive control P114596-WB-1-P
WB Recommended dilution 31 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human lung cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114596-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P114596(NQO1 Antibody) at dilution 1/35

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