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Full name | NQO1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Swissprot No | P15559 |
Gene Accession | NP_000894 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using P114596(NQO1 Antibody) at dilution 1/35 |
WB Positive control | P114596-WB-1-P |
WB Recommended dilution | 31 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human lung cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P114596-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P114596(NQO1 Antibody) at dilution 1/35
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