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Full name | NRAS rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
Swissprot No | P01111 |
Gene Accession | NP_002515. |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or NRAS antigen-treated (Neutralization experiment) using P114343(NRAS Antibody) at dilution 1/50 |
WB Positive control | P114343-WB-1-P |
WB Recommended dilution | 21 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm and Cell membrane |
IHC positive control | Positive control: Human breast cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P114343-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or NRAS antigen-treated (Neutralization experiment) using P114343(NRAS Antibody) at dilution 1/50
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