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Sku: P114343-50 μl

Specification

Full name NRAS rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Swissprot No P01111
Gene Accession NP_002515.
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or NRAS antigen-treated (Neutralization experiment) using P114343(NRAS Antibody) at dilution 1/50
WB Positive control P114343-WB-1-P
WB Recommended dilution 21 kDa
IHC predicted cell location Predicted cell location: Cytoplasm and Cell membrane
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114343-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or NRAS antigen-treated (Neutralization experiment) using P114343(NRAS Antibody) at dilution 1/50

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