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Sku: P102027-50 μl

Specification

Full name ABCG2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot No Q9UNQ0
Gene Accession NP_004818
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or ABCG2 antigen-treated (Neutralization experiment) using P102027(ABCG2 Antibody) at dilution 1/50
WB Positive control P102027-WB-1-P
WB Recommended dilution 72 kDa
IHC predicted cell location Predicted cell location: Cytoplasm and Cell membrane
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102027-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or ABCG2 antigen-treated (Neutralization experiment) using P102027(ABCG2 Antibody) at dilution 1/50

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