Bcakground Leptin is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the...
Bcakground Interleukin 23 is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of...
NGAL (Neutrophil Gelatinase-Associated Lipocalin) is a member of Lipocalin family sharing a highly conserved fold with an eight-stranded antiparallel beta barrel, and it acts as a transporters, carrying small molecules...
Interleukin 18 binding protein (IL-18 BP) is a secreted glycoprotein, which functions as an IL-18 antagonist by binding to IL-18 and blocking its biological activity. IL 18 BP bears no...
Description VEGF165 (Vascular Endothelial Growth Factor 165), one of the major isoforms of VEGF-A, functions as a disulfide-linked homodimer and plays a critical role in angiogenesis and cell culture. It...
Bcakground Erythropoietin (EPO)is a 34 kDa glycoprotein hormone in the type I cytokine family and is related to thrombopoietin (1). Its three N-glycosylation sites, four alpha helices, and N- to...
Bcakground Flt-3 Ligand(FLT3L)is an alpha-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages (1-3). Mature mouse Flt-3 Ligand consists of a 161 amino acid (aa) extracellular domain (ECD)...
Bcakground Sonic Hedgehog (Shh) is expressed in embryonic tissues that are critical for the patterning of the developing central nervous system, somite, and limb. It is also involved in whisker,...