Bcakground Interleukin-2 (IL-2) is an O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4⁺ and CD8⁺ T cells, γδ T...
Bcakground Interleukin-15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. (1, 2). Mature human IL-15...
Bcakground Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a name that designates two pleiotropic cytokines, IL-1...
CD28 homolog (CD28H), also called TMIG2 and IGPR-1, is a 55 kDa glycosylated transmembrane protein that shares approximately 10% amino acid (aa) sequence identity with CD28, CTLA-4, ICOS, and PD-1....
Bcakground The human AGT is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved...
Bcakground Interferon-alpha 2 (IFN alpha -2) is one of 14 subtypes within the IFN-alpha class of Type I Interferons (1). The members of the IFN-alpha class, also known as alpha...
Bcakground Interleukin-5 (IL-5)is a secreted glycoprotein that belongs to the alpha -helical group of cytokines (1 - 3). Unlike other family members, it is present as a covalently linked antiparallel...
The human Sftpd is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The protein may also be involved in surfactant metabolism.