AutoPlex-12 All-in-One Nucleic Acid Extraction & Real-Time PCR System

Sample-to-Result: Load the Sample, Get the Result

Nucleic acid extraction and real-time PCR run automatically in one closed instrument — 1–12 samples, up to 16 targets, results in as little as 30 minutes. Built-in touchscreen, no separate computer required.

Description

Conventional PCR testing runs through three separate steps — extraction, reaction setup and amplification — each with its own instrument, hands-on time and contamination risk. For labs that need results quickly, or that do not have dedicated PCR rooms, that workflow is the bottleneck.

The AutoPlex-12 combines magnetic bead nucleic acid extraction, real-time PCR amplification and 4-channel fluorescence detection in one closed instrument. Load the sample and pre-dispensed reagent strips, start the run, and get results in as little as 30 minutes. It processes 1–12 samples per run, with multiplex detection of up to 16 targets per sample. Runs are set up and results viewed on the built-in touchscreen, so no separate PC is needed.

The platform is open: it works with a wide range of fluorescent quantitative PCR reagent systems in both liquid and lyophilized formats. A sealing design using solid paraffin closes each reaction during amplification to reduce aerosol contamination.

How It Works

1. Load — add samples and pre-dispensed reagent strips; fit disposable magnetic rod covers.
2. Extract — the magnetic rod collects, transfers, incubates and elutes magnetic beads between reagent wells, without moving liquid between tubes.
3. Amplify — eluted nucleic acid is amplified in standard 200 µL PCR tubes on a Peltier thermal module, sealed with paraffin.
4. Detect — four LED excitation channels and a silicon photomultiplier read fluorescence in real time.

Why AutoPlex-12?

Integrated extraction-plus-PCR instruments generally fall into two groups: open systems that run your own reagents but take one to two hours per run, and closed cartridge systems that are fast but lock you into a proprietary assay menu. The AutoPlex-12 is designed to give you both speed and reagent freedom, in a stand-alone unit with its own touchscreen.

Comparison based on publicly available specifications for representative systems in each category; individual products vary.

Specifications

Features

• Sample-to-result automation — extraction, amplification and detection in one run, with minimal hands-on time.
• Fast — results in as little as 30 minutes.
• Built-in touchscreen — set up runs and review results directly on the instrument; no separate computer, saving bench space and IT setup.
• Multiplex — 4 fluorescence channels, up to 16 targets per sample.
• Contamination control — closed system, disposable rod covers and paraffin-sealed reactions.
• Open reagent platform — run your own or third-party qPCR assays, liquid or lyophilized.
• Compact benchtop footprint — fits in a biosafety cabinet or clean bench, and multiple units can be combined for higher throughput.
• Configurable for your region — power supply can be customized to local voltage and plug standards.

Applications

• Infectious disease research — respiratory, enteric and other pathogen panels.
• Public health and field laboratories — rapid testing where dedicated PCR rooms are not available.
• Border, customs and food inspection — on-site screening of samples.
• Veterinary and agricultural testing — animal and plant pathogen detection.
• Research labs — automated multiplex qPCR without separate extraction equipment.

Reagent Kits

FAQ