B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins. Mature human B7-H7 consists of a 322 amino acid (aa) extracellular...
A serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated...
Bcakground CCL2 , also called monocyte chemotactic protein-1 (MCP-1) or JE, is a member of the C-C or beta chemokine family that is best known as a chemotactic agent for...
CD28 homolog (CD28H), also called TMIG2 and IGPR-1, is a 55 kDa glycosylated transmembrane protein that shares approximately 10% amino acid (aa) sequence identity with CD28, CTLA-4, ICOS, and PD-1....
CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes....
Bcakground CD40 Ligand (CD40L), also known as TNFSF, CD154, TRAP, and gp39, is a 34–39 kDa type II transmembrane glycoprotein that belongs to the TNF superfamily (1–3). Mature human CD40...
CSF1 is a four-alpha -helical-bundle cytokine, the primary regulator of macrophage survival, proliferation and differentiation. It is also essential for the survival and proliferation of osteoclast progenitors, and primes and...
Bcakground Granulocyte Macrophage Growth Factor(GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. In response to cytokine or inflammatory stimuli, GM-CSF is...