Description BDTX-1535 is an orally bioavailable, brain-penetrating, mutation-selective, EGFR inhibitor with potential antitumor activity.BDTX-1535 is a fourth-generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR-mutant...

Description Preparing microbiological culture media requires a nutrient source with defined chemical characteristics and documented microbiological quality. Beef Extract Powder is prepared from very low-fat bovine skeletal muscle and marrow....

Description BI-2865 is a pan-KRAS inhibitor disables oncogenic signalling and tumour growth. BI-2865 blocks nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants,...

Description Biotin cadaverine, biotin-X cadaverine (90061), and biotin ethylenediamine (90057) can be coupled to carboxylic acids, DNA and other biomolecules. White solid soluble in DMSO Store at -20°C or 4°C...

Description Blue Dextran 2000 (CAS 87915-38-6) is a high-molecular weight polymer (average MW ~2,000,000 Da) covalently conjugated with Cibacron Blue dye, widely used as a premium void volume (V0) marker...

Description Bluo-Gal is a chromogenic substrate for β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates. Bluo-Gal is designed to...

Description: BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9...

  Description Reliable protein concentration measurement is an important step in routine biochemical workflows. Laboratories require a protein assay that is rapid, economical, easy to perform, and compatible with commonly...