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Specification
| Full name | VSIG8 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | VSIG8 (V-set and immunoglobulin domain-containing protein 8), also known as C1orf204, is a 414 amino acid single-pass type I membrane protein that contains two Ig-like V-type (immunoglobulin-like) domains. VSIG8 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q23.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. |
| Swissprot No | P0DPA2 |
| Gene Accession | BC132893 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or VSIG8 antigen-treated (Neutralization experiment) using P105503(VSIG8 Antibody) at dilution 1/240 |
| WB Positive control | P105503-WB-1-P |
| WB Recommended dilution | 44 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human brain |
| IHC Recommed dilution | Recommended dilution: 200-400 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P105503-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human brain tissue or VSIG8 antigen-treated (Neutralization experiment) using P105503(VSIG8 Antibody) at dilution 1/240
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