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Sku: P291626-50 μl

Specification

Full name UPF1 rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC, IF
Host Rabbit
Clone type rabbit monoclonal
Target Background This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Swissprot No Q92900
Gene Accession 5976
WB Predicted band size
WB Positive control P291626-WB-1-P
WB Recommended dilution 124 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human cholangiocarcinoma
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291626-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human cholangiocarcinoma tissue using P291626(UPF1 Antibody) at dilution 1/50

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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