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Sku: P113577-50 μl

Specification

Full name SAV1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Swissprot No Q9H4B6
Gene Accession BC020537
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or SAV1 antigen-treated (Neutralization experiment) using P113577(SAV1 Antibody) at dilution 1/90
WB Positive control P113577-WB-1-P
WB Recommended dilution 45 kDa
IHC predicted cell location Predicted cell location: Cytoplasm or Nucleus
IHC positive control Positive control: Human brain
IHC Recommed dilution Recommended dilution: 100-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P113577-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human brain tissue or SAV1 antigen-treated (Neutralization experiment) using P113577(SAV1 Antibody) at dilution 1/90

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