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Sku: P112046-50 μl

Specification

Full name RPS27A rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Swissprot No P62979
Gene Accession BC001392
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or RPS27A antigen-treated (Neutralization experiment) using P112046(RPS27A Antibody) at dilution 1/40
WB Positive control P112046-WB-1-P
WB Recommended dilution 18 kDa
IHC predicted cell location Predicted cell location: Nucleus and Cytoplasm
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 30-150

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P112046-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or RPS27A antigen-treated (Neutralization experiment) using P112046(RPS27A Antibody) at dilution 1/40

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