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Full name | NGEF rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity). |
Swissprot No | Q8N5V2 |
Gene Accession | BC031573 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or NGEF antigen-treated (Neutralization experiment) using P111493(NGEF Antibody) at dilution 1/35 |
WB Positive control | P111493-WB-1-P |
WB Recommended dilution | 82 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm or Nucleus |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 30-150 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P111493-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or NGEF antigen-treated (Neutralization experiment) using P111493(NGEF Antibody) at dilution 1/35
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