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Sku: P114519-50 μl

Specification

Full name HEXA rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Swissprot No P06865
Gene Accession BC018927
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or HEXA antigen-treated (Neutralization experiment) using P114519(HEXA Antibody) at dilution 1/100
WB Positive control P114519-WB-1-P
WB Recommended dilution 61 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 100-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114519-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or HEXA antigen-treated (Neutralization experiment) using P114519(HEXA Antibody) at dilution 1/100

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