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Full name | GLUD1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. |
Swissprot No | P00367 |
Gene Accession | NP_005262 |
WB Predicted band size | |
WB Positive control | P111728-WB-1-P |
WB Recommended dilution | 61 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 20-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P111728-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or GLUD1 antigen-treated (Neutralization experiment) using P111728(GLUD1 Antibody) at dilution 1/20
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