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Sku: P112017-50 μl

Specification

Full name FKBP1A rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
Swissprot No P62942
Gene Accession BC005147
WB Predicted band size
WB Positive control P112017-WB-1-P
WB Recommended dilution 12 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human tonsil
IHC Recommed dilution Recommended dilution: 40-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P112017-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or FKBP1A antigen-treated (Neutralization experiment) using P112017(FKBP1A Antibody) at dilution 1/55

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