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Full name | FKBP1A rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. |
Swissprot No | P62942 |
Gene Accession | BC005147 |
WB Predicted band size | |
WB Positive control | P112017-WB-1-P |
WB Recommended dilution | 12 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 40-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P112017-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or FKBP1A antigen-treated (Neutralization experiment) using P112017(FKBP1A Antibody) at dilution 1/55
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