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Sku: P114472-50 μl

Specification

Full name ESR1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain.
Swissprot No P03372
Gene Accession NP_000116
WB Predicted band size
WB Positive control P114472-WB-1-P
WB Recommended dilution 66 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P114472-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or ESR1 antigen-treated (Neutralization experiment) using P114472(ESR1 Antibody) at dilution 1/50

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Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

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