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Full name | CCR8 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. |
Swissprot No | P51685 |
Gene Accession | NP_005192 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or CCR8 antigen-treated (Neutralization experiment) using P102098(CCR8 Antibody) at dilution 1/20 |
WB Positive control | P102098-WB-1-P |
WB Recommended dilution | 41 kDa |
IHC predicted cell location | Predicted cell location: cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102098-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CCR8 antigen-treated (Neutralization experiment) using P102098(CCR8 Antibody) at dilution 1/20
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