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Product Name | Anti-CD68 antibody |
---|---|
Antibody Type | Primary Antibodies |
Immunogen | Polypeptide |
Clonality | Polyclonal |
---|---|
Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
WB:1:200-1:2000
IHC:1:200-1:1000 ICC/IF:1:100-1:500 |
|
Species Reactivity | |
Concentration | 1 mg/ml |
Purification | Protein A |
Gene Symbol | CD68 |
---|---|
Gene Synonyms |
GP110
LAMP4 SCARD1 |
Gene Full Name | CD68 molecule |
Gene Summary |
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
|
Molecular Weight(MW) | 37 kDa(Observed:52 kDa) |
Source | Rabbit |
Cellular Localization | Cell membrane and Endosome membrane. Lysosome membrane. |
Application Notes |
WB:1:200-1:2000 |
---|---|
IHC:1:200-1:1000 | |
ICC/IF:1:100-1:500 |
Form | Liquid |
---|---|
Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
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We also provide express shippping for time-sensitive deliveries.
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