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Sku: P291686-50 μl
Categories: Primary Antibodies

Specification

Full name ZYX rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC, IF
Host Rabbit
Clone type rabbit monoclonal
Target Background Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
Swissprot No Q15942
Gene Accession 7791
WB Predicted band size
WB Positive control P291686-WB-1-P
WB Recommended dilution 61 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human lung cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291686-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P291686(ZYX Antibody) at dilution 1/50

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

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