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Full name | ZNF131 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ERå (Estrogen receptor alpha)-mediated transactivation by interrupting ERå binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events. |
Swissprot No | P52739 |
Gene Accession | BC035875 |
WB Predicted band size | |
WB Positive control | P105694-WB-1-P |
WB Recommended dilution | 71 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human colorectal cancer |
IHC Recommed dilution | Recommended dilution: 25-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P105694-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or ZNF131 antigen-treated (Neutralization experiment) using P105694(ZNF131 Antibody) at dilution 1/30
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