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Sku: P105694-50 μl
Categories: Primary Antibodies

Specification

Full name ZNF131 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ERå (Estrogen receptor alpha)-mediated transactivation by interrupting ERå binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events.
Swissprot No P52739
Gene Accession BC035875
WB Predicted band size
WB Positive control P105694-WB-1-P
WB Recommended dilution 71 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human colorectal cancer
IHC Recommed dilution Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P105694-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or ZNF131 antigen-treated (Neutralization experiment) using P105694(ZNF131 Antibody) at dilution 1/30

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