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Sku: P103611-50 μl
Categories: Primary Antibodies

Specification

Full name UBR7 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr7 (ubiquitin protein ligase E3 component n-recognin 7), also known as C14orf130 or N-recognin-7, is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.
Swissprot No Q8N806
Gene Accession BC015046
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or UBR7 antigen-treated (Neutralization experiment) using P103611(UBR7 Antibody) at dilution 1/30
WB Positive control P103611-WB-1-P
WB Recommended dilution 48 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 30-150

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P103611-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or UBR7 antigen-treated (Neutralization experiment) using P103611(UBR7 Antibody) at dilution 1/30

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