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Sku: P112866-50 μl
Categories: Primary Antibodies

Specification

Full name TP63 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8.
Swissprot No Q9H3D4
Gene Accession NP_001316074
WB Predicted band size
WB Positive control P112866-WB-1-P
WB Recommended dilution 77 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human lung cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P112866-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or TP63 antigen-treated (Neutralization experiment) using P112866(TP63 Antibody) at dilution 1/65

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