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Sku: P104870-50 μl
Categories: Primary Antibodies

Specification

Full name TNFRSF1B rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Swissprot No P20333
Gene Accession BC052977
WB Predicted band size
WB Positive control P104870-WB-1-P
WB Recommended dilution 48 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P104870-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or TNFRSF1B antigen-treated (Neutralization experiment) using P104870(TNFRSF1B Antibody) at dilution 1/70

When can I expect my order to ship?

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