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Full name | TNFRSF1B rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. |
Swissprot No | P20333 |
Gene Accession | BC052977 |
WB Predicted band size | |
WB Positive control | P104870-WB-1-P |
WB Recommended dilution | 48 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human breast cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P104870-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or TNFRSF1B antigen-treated (Neutralization experiment) using P104870(TNFRSF1B Antibody) at dilution 1/70
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