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Sku: P103075-50 μl
Categories: Primary Antibodies

Specification

Full name TMPRSS11F rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
Swissprot No Q6ZWK6
Gene Accession NP_997290
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or TMPRSS11F antigen-treated (Neutralization experiment) using P103075(TMPRSS11F Antibody) at dilution 1/30
WB Positive control P103075-WB-1-P
WB Recommended dilution 49 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 25-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P103075-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or TMPRSS11F antigen-treated (Neutralization experiment) using P103075(TMPRSS11F Antibody) at dilution 1/30

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