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Full name | TAF11 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. |
Swissprot No | Q15544 |
Gene Accession | BC021972 |
WB Predicted band size | |
WB Positive control | P101190-WB-1-P |
WB Recommended dilution | 23 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human thyroid cancer |
IHC Recommed dilution | Recommended dilution: 35-150 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P101190-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or TAF11 antigen-treated (Neutralization experiment) using P101190(TAF11 Antibody) at dilution 1/40
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