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Specification
| Full name | STAT3 mouse monoclnal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | mouse monoclonal |
| Applications | WB, IHC |
| Host | Mouse |
| Clone type | mouse monoclonal |
| Target Background | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Swissprot No | P40763 |
| Gene Accession | |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human thyroid cancer and Human prostate cancer tissue using P113921(STAT3 Antibody) at dilution 1/150 |
| WB Positive control | P113921-WB-1-P |
| WB Recommended dilution | 88 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm or Nucleus |
| IHC positive control | Positive control: Human liver cancer and Human tonsil |
| IHC Recommed dilution | Recommended dilution: 100-500 |
Storage
Ascitic fluid with 0.05% sodium azide and 40% glycerol
WB PIC Description
P113921-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer and Human tonsil tissue using P113921(STAT3 Antibody) at dilution 1/150
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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