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Full name | SPRY2 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. |
Swissprot No | O43597 |
Gene Accession | BC015745 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or SPRY2 antigen-treated (Neutralization experiment) using P113508(SPRY2 Antibody) at dilution 1/200 |
WB Positive control | P113508-WB-1-P |
WB Recommended dilution | 35 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human colorectal cancer |
IHC Recommed dilution | Recommended dilution: 200-400 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P113508-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or SPRY2 antigen-treated (Neutralization experiment) using P113508(SPRY2 Antibody) at dilution 1/200
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