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Full name | SLC7A11 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
Swissprot No | Q9UPY5 |
Gene Accession | NP_055146 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or SLC7A11 antigen-treated (Neutralization experiment) using P103135(SLC7A11 Antibody) at dilution 1/65 |
WB Positive control | P103135-WB-1-P |
WB Recommended dilution | 55 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm and Cell membrane |
IHC positive control | Positive control: Human cervical cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P103135-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or SLC7A11 antigen-treated (Neutralization experiment) using P103135(SLC7A11 Antibody) at dilution 1/65
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