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Sku: P103135-50 μl
Categories: Primary Antibodies

Specification

Full name SLC7A11 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Swissprot No Q9UPY5
Gene Accession NP_055146
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or SLC7A11 antigen-treated (Neutralization experiment) using P103135(SLC7A11 Antibody) at dilution 1/65
WB Positive control P103135-WB-1-P
WB Recommended dilution 55 kDa
IHC predicted cell location Predicted cell location: Cytoplasm and Cell membrane
IHC positive control Positive control: Human cervical cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P103135-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or SLC7A11 antigen-treated (Neutralization experiment) using P103135(SLC7A11 Antibody) at dilution 1/65

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