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Full name | SIGLEC5 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
Swissprot No | O15389 |
Gene Accession | BC029896 |
WB Predicted band size | |
WB Positive control | P100703-WB-1-P |
WB Recommended dilution | 61 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P100703-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or SIGLEC5 antigen-treated (Neutralization experiment) using P100703(SIGLEC5 Antibody) at dilution 1/55
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