Recombinant Mouse SHH

Description

Mouse SHH is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. Mouse SHH shares 99% homology with the human gene for SHH. Sonic HedgeHog is a protein that is vital in guiding the early embryo; it has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. SHH binds to the patched receptor to activate the transcription of target genes. Sonic HedgeHog also regulates another factor, the gli oncogene. Recombinant Mouse SHH is a single, non-glycosylated polypeptide chain of 19.8 kDa.

Note: Recombinant Mouse SHH is suitable for mouse cell culture, stem cell differentiation, neural patterning, and Sonic Hedgehog signaling studies. It may be used in research workflows involving Cell Biologics cell culture systems or related mouse cell models, with protocol conditions optimized by the user.