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$420.00
Sku: Y07001H-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 20, 2026
Description
PDGF-AA (Platelet-Derived Growth Factor-AA), a subtype of the platelet-derived growth factor (PDGF) family, consists of two identical A chains. It primarily regulates cellular processes such as proliferation, migration, differentiation, and survival by activating tyrosine kinase receptors on the cell membrane (PDGFR-αα, PDGFR-αβ, or PDGFR-ββ). PDGF-AA specifically binds to the PDGFR-αα receptor and stimulates the proliferation of specific cell types, including fibroblasts, glial cells, and mesenchymal stem cells (MSCs), making it widely used for expanding primary or hard-to-culture cells. In wound healing and tissue engineering research, PDGF-AA can induce directed cell migration to mimic in vivo repair processes. For certain mesenchymal stem cells or neural precursor cells, it helps maintain their undifferentiated state or promotes directed differentiation—such as toward osteogenic or glial lineages.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y07001H |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | The bioactivity is determined by the dose-dependent proliferation of NIH3T3 cells is typically between ≤5.0 ng/mL. |
| Accession | P04085 |
| Alternative Names | Platelet-derived growth factor subunit A; PDGF-1 |
| Species | Human |
| Expression System | CHO |
| Target Protein Sequence | Ser87-Thr211 |
| Mol. Weight | 14.3kDa |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Supports mesenchymal stem cell proliferation and migration.
Cell Biology
Stimulates fibroblast proliferation, migration, and tissue remodeling.
Data Figures
Figure 1: Measured in a cell proliferation assay using NIH3T3 cells.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
