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Sku: GMP-TL511-0050

Description

Recombinant Human Interleukin-3 (IL-3) is a crucial cytokine involved in the regulation of hematopoiesis, stimulating the proliferation and differentiation of various blood cells. IL-3 exerts its effects by binding to the IL-3 receptor, initiating signaling pathways that are essential for the development and function of the immune system. This makes it a valuable tool for research in immunology, hematology, and cell biology.

Specifications

Cytokines Details
Expression Host A DNA sequence encoding the human IL-3 (GenBank: AAA59146.1) was expressed with a His-tag at the C-terminus.
Synonym MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
Protein Sequence The recombinant human IL-3 protein consists of 139 amino acids.
Molecular Mass Predicts a molecular mass of 15.9 kD.
QC Testing Purity > 95% as determined by SDS-PAGE.
Endotoxin HEK293 cells (Host verification)
Formulation Lyophilized powder.
Stability Store at -20°C or below to maintain product stability and activity. Avoid repeated freeze-thaw cycles.
Storage Stable for long-term storage under recommended conditions, ensuring reliable performance.

Features

  • High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%, ensuring the reliability and reproducibility of experimental results.
  • High Biological Activity: Verified through multiple activity assays, this product effectively induces the expected biological responses in target cells.
  • Batch Consistency: Manufactured under strict production and quality control protocols to ensure high consistency between batches.
  • Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.

Applications

Hematology

Research the role of IL-3 in the regulation of blood cell production and mechanisms of hematopoiesis.

Immunology

Study the effects of IL-3 on immune cell development and function in immune response.

Stem Cell Research

Utilize IL-3 in studies focusing on stem cell differentiation and proliferation.

Cell Biology

Investigate the impact of IL-3 on cell signaling pathways, survival, and proliferation.

Data Figures

Recombinant Human IL-3 Protein

Figure 1: Recombinant Human IL-3 Protein Analysis

Instructions for Use

  • Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
  • Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
  • Do not mix with other similar products to avoid cross-reactivity and potential interference.

Cautions

• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.

• Preservation: Handle according to instructions to preserve its activity and stability.

• Support: Contact our technical support team if you encounter any issues or questions.

Documents

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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