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$83.00
Sku: Y01801-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 18, 2026
Description
IFN-γ (Interferon-gamma) is a cytokine produced by immune cells such as T cells and NK cells, belonging to the type II interferon family. It plays a central role in immune regulation, antiviral and antitumor responses, and immune defense. IFN-γ induces the production of antiviral proteins (e.g., PKR, OAS) that inhibit viral replication and enhances the phagocytic and pathogen-killing capacity of macrophages. In terms of cell proliferation and apoptosis, IFN-γ suppresses the growth of certain tumor cells and promotes their apoptosis. In stem cell culture, it inhibits the adipogenic differentiation of mesenchymal stem cells (MSCs) while promoting osteogenic differentiation.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y01801 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a cell proliferation assay using Mo7e human leukemia cell line. The ED50 for this effect is ≤ 2 ng/mL. |
| Accession | P01579 |
| Alternative Names | Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 16.8 kDa |
| Expression Region | Gln24-Gln166 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Hematology
Modulates hematopoietic progenitor differentiation under inflammatory conditions.
Immunology
Key cytokine for Th1 responses, activates macrophages and NK cells.
Stem Cell Research
Used to stimulate immune-like differentiation in stem cell cultures.
Cell Biology
Regulates cell proliferation, apoptosis, and immune signaling.
Data Figures
Figure 1: Recombinant Human IFNγ (Cat. No. Y01801) SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y01801 SDS-PAGE.
Figure 2: Recombinant Human IFNγ (Cat. No. Y01801) stimulates proliferation of Mo7e cells. The ED50 for this effect is ≤2 ng/mL. The bioactivity of Y01801 was higher than the other competing product.
Figure 3: Highly consistent bioactivity between different production batches of Recombinant Human Transferrin (Cat. No. Y01801).
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
