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$348.00
Sku: Y00101N-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 18, 2026
Description
Activin A is a dimeric glycoprotein belonging to the transforming growth factor-beta (TGF-β) superfamily, composed of two inhibin β subunits. It can be expressed by various cells in the body, such as endothelial cells, macrophages, and dendritic cells. As a pleiotropic factor, Activin A is widely expressed in tissues and participates in regulating the functions of multiple biological systems, including embryogenesis, cell growth and differentiation, as well as immune and inflammatory responses.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y00101N |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific bioactivity of ≥ 5 x 105 units/mg. |
| Accssion | P08476 |
| Alternative Names | Activin beta-A chain; Erythroid differentiation protein; EDF |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 12.9 kDa |
| Expression Region | Gly311-Ser426 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | Lyophilized from a 0.22 μm-filtered solution containing 0.085% TFA, 30% ACN, 5% Mannitol, pH2.5. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in 4 mM HCl. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Hematology
Modulates erythroid and myeloid progenitor differentiation.
Immunology
Regulates immune cell differentiation and inflammatory responses.
Stem Cell Research
Maintains pluripotency of ESCs/iPSCs and guides mesendoderm differentiation.
Cell Biology
Controls cell proliferation, differentiation, and apoptosis via SMAD2/3 signaling.
Data Figures
Figure 1: Recombinant Human Activin A (Cat. No. Y00101N) SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y00101N SDS-PAGE.
Figure 2: Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/mL, corresponding to a specific bioactivity of ≥ 5 x 105 units/mg.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
