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Specification
| Full name | RBFOX1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Swissprot No | Q9NWB1 |
| Gene Accession | NP_001135805 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or RBFOX1 antigen-treated (Neutralization experiment) using P106453(RBFOX1 Antibody) at dilution 1/50 |
| WB Positive control | P106453-WB-1-P |
| WB Recommended dilution | 43 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P106453-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or RBFOX1 antigen-treated (Neutralization experiment) using P106453(RBFOX1 Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
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