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Full name | Rb1 rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and enzyme binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; negative regulation of myofibroblast differentiation; and negative regulation of transcription involved in G1/S transition of mitotic cell cycle. Acts upstream of or within several processes, including hepatocyte apoptotic process; neuron development; and regulation of transcription by RNA polymerase II. Located in nucleus and spindle. Part of Rb-E2F complex. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; retina; and vibrissa. Human ortholog(s) of this gene implicated in nervous system cancer (multiple); osteosarcoma; prostate cancer; small cell carcinoma; and urinary bladder cancer. Orthologous to human RB1 (RB transcriptional corepressor 1). [provided by Alliance of Genome Resources, Apr 2022] |
Swissprot No | P13405 |
Gene Accession | 19645 |
WB Predicted band size | |
WB Positive control | P291735-WB-1-P |
WB Recommended dilution | 105 kDa |
IHC predicted cell location | |
IHC positive control | |
IHC Recommed dilution |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P291735-WB-1-P
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