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Specification
| Full name | RAD23B rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Swissprot No | P54727 |
| Gene Accession | BC020973 |
| WB Predicted band size | |
| WB Positive control | P104401-WB-1-P |
| WB Recommended dilution | 43 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus and Cytoplasm |
| IHC positive control | Positive control: Human lung cancer |
| IHC Recommed dilution | Recommended dilution: 30-150 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P104401-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or RAD23B antigen-treated (Neutralization experiment) using P104401(RAD23B Antibody) at dilution 1/25
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We also provide express shippping for time-sensitive deliveries.
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