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Sku: P104808-50 μl

Specification

Full name PRKCA rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Swissprot No P17252
Gene Accession BC109273
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or PRKCA antigen-treated (Neutralization experiment) using P104808(PRKCA Antibody) at dilution 1/55
WB Positive control P104808-WB-1-P
WB Recommended dilution 77 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human colorectal cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P104808-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or PRKCA antigen-treated (Neutralization experiment) using P104808(PRKCA Antibody) at dilution 1/55

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