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Full name | PRC1 (phospho-Thr481) rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB, IHC, IF |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
Swissprot No | O43663 |
Gene Accession | 9055 |
WB Predicted band size | |
WB Positive control | P291204-WB-1-P |
WB Recommended dilution | 72 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm and Nucleus |
IHC positive control | Positive control: Human lung cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P291204-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P291204(PRC1 (phospho-Thr481) Antibody) at dilution 1/50
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