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Sku: P115165-50 μl
Categories: Primary Antibodies

Specification

Full name PON2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Swissprot No Q15165
Gene Accession BC046160
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or PON2 antigen-treated (Neutralization experiment) using P115165(PON2 Antibody) at dilution 1/80
WB Positive control P115165-WB-1-P
WB Recommended dilution 39 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P115165-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or PON2 antigen-treated (Neutralization experiment) using P115165(PON2 Antibody) at dilution 1/80

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